GO:0004839 molecular_function ubiquitin activating enzyme activity
| PAG Title | GO:0004839 molecular_function ubiquitin activating enzyme activity |
| PAG ID | TAX015431 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 0 |
| Information Content | Poor |
| Other IDs | GO:0004839 |
| Base PAG ID | TAX015431 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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